AN IMPROVED PREPARATION OF ω-HYDROXY ALIPHATIC ACIDS AND THEIR ESTERS
نویسندگان
چکیده
منابع مشابه
Highly efficient macrolactonization of ω-hydroxy acids using benzotriazole esters: synthesis of Sansalvamide A.
A facile and mild macrolactonization reaction of ω-hydroxy acids was developed based on the transesterification of benzotriazole esters. Treatment of ω-hydroxy acids with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) and 1-hydroxy benzotriazole (HOBT) in chloroform provided macrolactones in excellent yields. The reactions were performed under basic, neutral and acidic conditions using N,...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1960
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v60-266